Pandemic 2020

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DIY-HP-LED

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The CDC announced this week that the BA.2 Omicron variant, which is reportedly 30% more transmissible than the original BA.1 Omicron strain — has become dominant among new cases sequenced in the United States. That’s a startling rise for a variant that was less than 1% of all sequences as recently as January. But, just as Americans are hearing about BA.2, there’s already a newer, even more transmissible variant on the rise.

There are actually three new variants that have been given designations. According to a recently-released report from the UK Health Services Agency, the two being called XD and XF are combinations of Delta and BA.1, or so-called “Deltacron” strains, which have been talked about for months but made no significant inroads in any country.
 
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CCGNZ

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The CDC announced this week that the BA.2 Omicron variant, which is reportedly 30% more transmissible than the original BA.1 Omicron strain — has become dominant among new cases sequenced in the United States. That’s a startling rise for a variant that was less than 1% of all sequences as recently as January. But, just as Americans are hearing about BA.2, there’s already a newer, even more transmissible variant on the rise.

There are actually three new variants that have been given designations. According to a recently-released report from the UK Health Services Agency, the two being called XD and XF are combinations of Delta and BA.1, or so-called “Deltacron” strains, which have been talked about for months but made no significant inroads in any country.

XD is present in several European countries, but has not been detected in the UK, according to the report. XF caused a small cluster in the UK but has not been detected there since February 15. The variant of greater concern, it seems, is the one dubbed XE.

Like the other two new arrivals, XE is a recombinant strain, meaning it is made up of two previously-distinct variants. But it is not a Deltacron mix. XE is actually made up of the original Omicron (BA.1) and the newer Omicron (BA.2) which has taken over in the U.S.

Omicron BA.2 Variant Now Dominant In U.S.; Hitting Northeast Hard

The World Health Organization issued a report yesterday with some preliminary findings about XE.

“The XE recombinant was first detected in the United Kingdom on 19 January and >600 sequences have been reported and confirmed since,” reads the WHO document. “Early-day estimates indicate a community growth rate advantage of ~10% as compared to BA.2, however this finding requires further confirmation.”

Further confirmation is getting more difficult by the day, according to WHO, which registered concern this week at what it calls “the recent significant reduction in SARS-CoV-2 testing by several Member States. Data are becoming progressively less representative, less timely, and less robust. This inhibits our collective ability to track where the virus is, how it is spreading and how it is evolving: information and analyses that remain critical to effectively end the acute phase of the pandemic.”

Covid BA.2 Omicron Variant Likely Now Accounts For Majority Of New Cases In Los Angeles





Last week’s briefing from the UK Health Services Agency reinforces some of the WHO report’s assertions and urges caution about jumping to conclusions. One difference between the two documents is that the WHO data and analysis seems to be more recent.

From the UK HSA briefing:

XE shows evidence of community transmission within England, although it is currently less >1% of total sequenced cases. Early growth rates for XE were not significantly different from BA.2, but using the most recent data up to 16 March 2022, XE has a growth rate 9.8% above that of BA.2. As this estimate has not remained consistent as new data have been added, it cannot yet be interpreted as an estimate of growth advantage for the recombinant. Numbers were too small for the XE recombinant to be analysed by region.

To be clear, XE only accounts for a tiny fraction of cases worldwide. That may change, given that XE is thought to be about 10% more transmissible than the already more-transmissible BA.2. That means it may be roughly 43% more transmissible than the original Omicron that savaged the globe last winter.

But a new wave of infections from the now-dominant BA.2 has not materialized, even as restrictions have been eased. So hopefully the trend with XE, should it out-compete BA.2, will be similar. Only time — and good surveillance — will tell.
:oI just booked booster #2 for April 16,as anyone 50 or older can get one in the US,I guess I'm just nervous about the pandemic now in the backseat w/Ukraine now in the spotlight,people seem pretty care free now and I can't say I blame them as this whole thing is tiresome,but I'm not comfortable letting my guard down yet as unpredictability has been the rule in this whole thing.
 

DIY-HP-LED

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Epstein-Barr virus as a driver of multiple sclerosis

Accumulating evidence implicates Epstein-Barr virus (EBV) as an etiological factor in multiple sclerosis (MS). If EBV is a “driver” that causes antiviral immunity with associated autoimmune components rather than a “trigger” that unleashes self-perpetuating autoimmunity, then elimination of EBV would be a rational therapy for MS.
 

captainmorgan

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I wanted to schedule my second booster yesterday so I went to the county health dept website. To my surprise there is no wait what so ever and they listed openings for any day next week even tho the number of locations giving vaccines has gone down. When I got my 1st booster in early December I had to wait weeks for a appointment. I didn't schedule a appointment since I would like to wait till mid May for my second booster and keep them 6 months apart. I checked and only 36% of the state has had the first booster, I guess the herd has bought into the covid is over bullshit, you can't fix stupid.
 

Roger A. Shrubber

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injinji

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My drama of choice involves death every episode. Father Brown does it for me. It's basically all I watch (other than Monk on Sunday nights at the riverhouse) Someone always dies. The cops get the wrong guy. Father Brown solves it and it's all over in 45 minutes.

 

Roger A. Shrubber

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12Monkeys stands out in my mind as traumatic. I wish I’d never seen it. Fifth Element is light enough, and I enjoyed the opener with that beetle of a ship. I have been known to shout AZIZ! LIGHT!
really? i don't recall it being traumatic...the only movie i ever felt traumatized by is Eraserhead...that is a seriously fucked up movie.
Aziz!.gif
merde, je ne savais pas que c'était en français...
 

CCGNZ

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Cases spreading in Shanghai despite a hard lock down, looks like they have lost control, 13,000 cases yesterday.
Things have a way of going full circle,it started in China and wasn't nearly as infectious as the new variants so they're brutal lockdown tactics worked,now the Chinese will probably mutate it into something even more deadly and launch it all over again,hope I'm wrong but it sure would be ironic.
 

CCGNZ

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Sincerely hope I'm wrong,more than 2 yrs. already,2nd booster in 2 wks and I'm in really good phys.shape at 56,but this is starting to get tiresome and sickening,the only thing that takes it off the radar is the insanity in Ukraine.
 

Wattzzup

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Covid is like cancer. Companies are getting rich treating it. Not curing it.

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Based on company financial statements, the Alliance estimates that Pfizer, BioNTech and Moderna will make pre-tax profits of $34 billion this year between them, which works out as over a thousand dollars a second, $65,000 a minute or $93.5 million a day. The monopolies these companies hold have produced five new billionaires during the pandemic, with a combined net wealth of $35.1 billion.
 
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