Pandemic 2020

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printer

Well-Known Member
I like this guy as he puts the science in a form us ordinary people can consume. Mind you I get what he says and wish he cuts down the presentation by half the time. A paper came out on deformed cells in the bloodstream and why they may cause the Long Haul effect in some people. The paper link is in the video's description.

Long-term changes to blood cells triggered by Covid-19 infection

 

Sativied

Well-Known Member
I hope so. If the hospitalizations and deaths remain low, we could be on the way out of this.
Right, best case scenario it'll show to be a too early poorly executed exit strategy. Worst case scenario we're all gonna die from a Dutch variant. It usually takes a week or longer for infected to be potentially hospitalized, and weeks more for them to potentially die so it's really hard to say at this point. We have a relatively low number of ICU units for our population, the remaining capacity has been the major dictating factor for new restrictions and lockdowns. Out of 1200 ICU beds, 75 are now occupied (9 less than yesterday). That's the lowest since sep last year..... ....at the start of the second wave. Given the high vaccination rates among the elder, and the majority of cases being youngsters it's very unlikely it will overwhelm hospitals again.

@Sativied Looks like you have a big problem started there.


View attachment 4942759
Because the daily average exceeds the weekly average that line is still going up. In absolute numbers however, cases dropped ~25% from the most recent peak already, within a few days. 65% of new cases were contracted at clubs, parties etc. The whole 'Dansen [dancing] after Janssen' campaign is responsible for a large portion of the direct cases. Specifically, being able to enter clubs etc the day after the J&J shot. This has been increased to 2 weeks and was more strictly enforced last weekend.

When you zoom in on the last 5 weeks of that graph it paints a different picture:
Screen Shot 2021-07-13 at 18.37.12.png

Usually today is around the peak of the week (less testing in weekend). It would be a first if that changes.

Obviously it's bad either way but it's in practice not a big problem yet and heading in the right direction again. The government apologized for fucking up, they expected a rise similar to UK but not this quickly.

No, I tried to lead down the garden path with progressively worse remarks. And that is the problem with a number of them being used. It is not that they are all wrong, it is that they are not said with any context and one little scrap of information is used to discount all that has been done. One silly thing is they use the current numbers and say, "We could live with this level of deaths, we do not need the methods in place used to reduce the spread." Yes but the number would be worse if we did not employ the methods. A little fact that is omitted.
Yes sure, not arguing. At some point however, like we have in NL now, pretty much all restrictions are gone and within the next few weeks or months even we'll know what level of deaths there will be without all the restrictions. Same in UK starting next week. Covid isn't going away, and we can't / don't want to force vaccination on 100% of the population, there's going to be a point where we got to live with it.
 

injinji

Well-Known Member
"You test more you are going to get more cases."

"The number of cases does not mater as long as they are not in the hospital."

"The people in the hospital are not a problem with the treatments to treat the virus."

"99.99% of people recover anyway."

"The numbers are fake."
You forgot "they were all old anyway."
 

DIY-HP-LED

Well-Known Member
This might make a big difference in the developing world.
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Quarter-dose of Moderna COVID vaccine still rouses a big immune response (nature.com)

Quarter-dose of Moderna COVID vaccine still rouses a big immune response
Results hint that dose stretching could help to address the world’s acute vaccine shortage.

A little bit of coronavirus vaccine goes a long way towards generating lasting immunity.

Two jabs that each contained only one-quarter of the standard dose of the Moderna COVID-19 vaccine gave rise to long-lasting protective antibodies and virus-fighting T cells, according to tests in nearly three dozen people1. The results hint at the possibility of administering fractional doses to stretch limited vaccine supplies and accelerate the global immunization effort.

Since 2016, such a dose-reduction strategy has successfully vaccinated millions of people in Africa and South America against yellow fever2. But no similar approach has been tried in response to COVID-19, despite vaccine shortages in much of the global south.

“There’s a huge status quo bias, and it’s killing people,” says Alex Tabarrok, an economist at George Mason University in Fairfax, Virginia. “Had we done this starting in January, we could have vaccinated tens, perhaps hundreds, of millions more people.”

The just-right dose?
In the earliest trial of Moderna’s mRNA-based vaccine, study participants received one of three dose levels: 25, 100 or 250 micrograms3. The top dose proved too toxic. The low dose elicited the weakest immune response. The middle dose seemed to offer the best balance: it triggered strong immunity and had acceptable side effects.

That 100-microgram dose ultimately became the one authorized for mass use in dozens of countries. But Moderna scientists later showed that a half-dose seemed to be just as good as the standard dose at stimulating immune protection4.

To find out whether a low dose might offer protection, scientists analysed blood from 35 participants in the original trial. Each had received two 25-microgram jabs of vaccine 28 days apart.

Six months after the second shot, nearly all of the 35 participants had ‘neutralizing’ antibodies, which block the virus from infecting cells, the researchers reported in a preprint published on 5 July1. Participants’ blood also contained an armada of different T cells, both ‘killer’ cells that can destroy infected cells and a variety of ‘helper’ cells that aid in general immune defence.
...
 

PJ Diaz

Well-Known Member
This might make a big difference in the developing world.
-----------------------------------------------------------------------------------------------------------------------------
Quarter-dose of Moderna COVID vaccine still rouses a big immune response (nature.com)

Quarter-dose of Moderna COVID vaccine still rouses a big immune response
Results hint that dose stretching could help to address the world’s acute vaccine shortage.

A little bit of coronavirus vaccine goes a long way towards generating lasting immunity.

Two jabs that each contained only one-quarter of the standard dose of the Moderna COVID-19 vaccine gave rise to long-lasting protective antibodies and virus-fighting T cells, according to tests in nearly three dozen people1. The results hint at the possibility of administering fractional doses to stretch limited vaccine supplies and accelerate the global immunization effort.

Since 2016, such a dose-reduction strategy has successfully vaccinated millions of people in Africa and South America against yellow fever2. But no similar approach has been tried in response to COVID-19, despite vaccine shortages in much of the global south.

“There’s a huge status quo bias, and it’s killing people,” says Alex Tabarrok, an economist at George Mason University in Fairfax, Virginia. “Had we done this starting in January, we could have vaccinated tens, perhaps hundreds, of millions more people.”

The just-right dose?
In the earliest trial of Moderna’s mRNA-based vaccine, study participants received one of three dose levels: 25, 100 or 250 micrograms3. The top dose proved too toxic. The low dose elicited the weakest immune response. The middle dose seemed to offer the best balance: it triggered strong immunity and had acceptable side effects.

That 100-microgram dose ultimately became the one authorized for mass use in dozens of countries. But Moderna scientists later showed that a half-dose seemed to be just as good as the standard dose at stimulating immune protection4.

To find out whether a low dose might offer protection, scientists analysed blood from 35 participants in the original trial. Each had received two 25-microgram jabs of vaccine 28 days apart.

Six months after the second shot, nearly all of the 35 participants had ‘neutralizing’ antibodies, which block the virus from infecting cells, the researchers reported in a preprint published on 5 July1. Participants’ blood also contained an armada of different T cells, both ‘killer’ cells that can destroy infected cells and a variety of ‘helper’ cells that aid in general immune defence.
...
As I mentioned previously in a different thread, Moderna didn't come up with the amount of the dosage amount based on a scientific study. There were basically two camps of thought within Moderna; one camp thought that 50mcg was a good amount, and the other camp wanted to go with 200mcg, so they basically split the difference. Not too surprising since this is still experimental.
 

Dr.Amber Trichome

Well-Known Member
As I mentioned previously in a different thread, Moderna didn't come up with the amount of the dosage amount based on a scientific study. There were basically two camps of thought within Moderna; one camp thought that 50mcg was a good amount, and the other camp wanted to go with 200mcg, so they basically split the difference. Not too surprising since this is still experimental.
How are you going to avoid the delta variant?
 

PJ Diaz

Well-Known Member
That’s it? No mask? Good luck. It’s hunting for your virgin T-cells, and it’s quite determined to find your dumb ass.
I wear a mask indoors when around other people as a courtesy. Taking a T-cell detect test is a great way to determine if you have natural immunity. It's been shown that people who have gotten the vax and people who have previously been infected have essentially the same chance of reinfection.



Screenshot (88).png
 

Dr.Amber Trichome

Well-Known Member
I wear a mask indoors when around other people as a courtesy. Taking a T-cell detect test is a great way to determine if you have natural immunity. It's been shown that people who have gotten the vax and people who have previously been infected have essentially the same chance of reinfection.



View attachment 4943834
Each individual has a different level of immunity after getting the virus. Some have immunity longer than others. What’s the length of your immunity?
 

PJ Diaz

Well-Known Member
Each individual has a different level of immunity after getting the virus. Some have immunity longer than others. What’s the length of your immunity?
At this point that is as much of a question as is the length of protection from the vaccine. That said I'm happy to get a T-detect test every 6 months to confirm continuous immunity. I should say however that t cells from the first SARS virus have been shown to last over a decade.
 

Dr.Amber Trichome

Well-Known Member
At this point that is as much of a question as is the length of protection from the vaccine. That said I'm happy to get a T-detect test every 6 months to confirm continuous immunity. I should say however that t cells from the first SARS virus have been shown to last over a decade.
What do you suggest a person to do if they have not had the first SARS virus ? Get the vaccine or get infected and possible die ?
 

CunningCanuk

Well-Known Member

Jimdamick

Well-Known Member
I don't know if anyone remembers my snide remark that I made a few weeks ago that we ain't seen nothing yet & there are more letters in the Greek alphabet available to name the future variants of the Alpha, Covid-19.
Delta was the next one used.
Now we have the next letter used for the latest variant which was formed in Peru in December, 2020.
Lamda is it's name and it was designated a "variant of interest" in June by the World Health Organization.
It differs from Covid-19 & Delta in that along with damage to the lungs, it causes neurological damage.
It has spread to at least 30 countries around the world and may be more resistant to COVID-19 vaccines compared to other strains. It is also suggested that the Lambda variant is more infectious than Covid-19 or the Gamma variant.
Fucking excellent, right?
And it ain't even fall yet when these fuckers are supposed to really take off.
Wear a mask & social distance & try to stay safe.
Don't believe the hype that it again is safe to go to bars/restaurants & parties.
It isn't.
Good luck/Peace out
 
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PJ Diaz

Well-Known Member
What do you suggest a person to do if they have not had the first SARS virus ? Get the vaccine or get infected and possible die ?
The first SARS virus has nothing to do with SARS CoV-2, so not sure what you're on about.
You’re getting it, peej. It’s guaranteed. Hopefully it doesn’t kill you. Maybe you’ll be lucky and get a double lung transplant, like this guy:

I've already had it, that's how you get t cells, dummy.
 

Jimdamick

Well-Known Member
You’re getting it, peej. It’s guaranteed. Hopefully it doesn’t kill you. Maybe you’ll be lucky and get a double lung transplant, like this guy:

I read the story about that nitwit.
He went to Florida like a fool.
His whole family got the vacination (they're fine) & he refused to follow suit because he was concered there might be side effcts
The dumb fuck said he was going to wait a "couple of years" before he got the shot.
I found this funny in my fucked up brain,
As they were wheeling him into the emergency room he asked if he could get the shot now, and the nurse had to tell him, nope, it's too late now, you jerk, you got it now, have fun :) (Well, that actually is not what was said, but I bet the nurse was thinking it).
 
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Dr.Amber Trichome

Well-Known Member
I don't know if anyone remembers my snide remark that I made a few weeks ago that we ain't seen nothing yet & there are more letters in the Greek alphabet avaiable to name the future variants of the Alpha, Covid-19.
Delta was the next one used.
Now we have the next letter used for the latest variant which was formed in Peru in December, 2020.
Lamda is it's name and it was designated a "variant of interest" in June by the World Health Organization.
It differs from Covid-19 & Delta in that along with damage to the lungs, it causes neurological damage.
It has spread to at least 30 countries around the world and may be more resistant to COVID-19 vaccines compared to other strains. It is also suggested that the Lambda variant is more infectious than Covid-19 or the Gamma variant.
Fucking excellent, right?
And it ain't even fall yet when these fuckers are supposed to really take off.
Wear a mask & social distance and try to stay safe.
Don't believe the hype that it again is safe to go to bars/restaurants & parties.
It isn't.
Good luck/Peace out
Yeah, I agree . It’s not safe at all. My husband and I were talking about how we ( both fully vaccinated) are going to be back on full protective pandemic mode like in the beginning. Mask up everywhere and social distancing avoiding crowds and being on alert in all public places. It’s not safe and i have direct Patient contact with lots of patients that refuse to get vaccinated . I treat at them now like they are 100% infected and find their attitudes quite upsetting .
 
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