Using cannabis is such a joyful and important hourly event in my life I would get really depressed without it for that long. The most I go it a day without smoking, like 8-10 hrs at the most. (But I'm on extremely potent oil as well) Even with the oil I'm almost on edge without a hit, not in a bad way but like itching for it, I really cant wait! If I went 2 days I would be 100% miserable, however I use it for chronic pain which links to depression if not treated daily.
What do you use it for? Do you have depression even when smoking?