I've had the same thought myself. I relocated a few months ago, don't have a hookup and haven't spoken to a kind MD yet, so started buying the stuff as a substitute. After going through a few grams (I tried Pep Spice, Voodoo, and K4 Diamond. The Pep and K4 were respectable, Voodoo gave me a headache, but none lasted more than 20 or 30 minutes), a kind soul hooked me up with a gram of Blue Dream with the promise that it would "knock me flat on my ass". I went through the whole gram a la bong and barely got high. JWH is a cannabinoid receptor agonist, so should lead to tolerance. I'm a biochemist so know of plenty of compounds that are irreversible agonists, essentially the receptor involved is shot until you make new ones, hopefully that isn't the case with this stuff. I don't know about the year figure quoted above, but I don't know that much about the cannabinoid receptor (or any other neuroreceptors for that matter) - does anyone know the turnover rate for the cannabinoid receptor? Hopefully it doesn't bind with high affinity or irreversibly, I'd like to enjoy the good herb to the best of it's potential again. I'd be interested in hearing from anyone else with knowledge or experience - what can I expect from the tolerance JHW products cause?