I've never sprayed my buds, then again I've never had mites or PM. The only form of prevention I employ is biological. If the right microbes are proliferating they choke out the ability of the wrong ones to ever take hold.
Foliar spray with LAB, cyanobacteria, Purple sulfur bacteria, yeasts. Soil drench with them too. Always include Trichoderma in the soil, your plants SAR will be sky high coupled with the SAR inducing phototropic bacterial from the sprays.
Foliar in veg, so you won't have to in flower. Continue soil drenching
I can't speak for remediation of PM as I've never had it indoors or on cannabis ever.