I'm on my first grow ever, so take my knowledge and experience with a grain of salt. Growing in straight coco with General Organics nutrients. I feed or water daily; pH with coco is best at 5.8 but I range 5.5-6.2. If it's a day I am adding Cal/Mg supplement, I keep the pH on the higher side of the range because I read that it's better absorbed that way. If I have free time and think of it, I might water plants a 2nd time in a day -- they seem to tolerate it well in coco and in their late blooming stage. The more mature the plants become, the more they seem to receive more frequent and higher concentration of nutes. When I first started out, I was not checking pH and I had some problems. Ever since, the only problem has been trying to get the perfect concentration of nutes to prevent nute burn but provide enough food. My three plants are almost finished. Will probably be harvesting the tops this week, then let the rest of her go for 2 more weeks. Happy with the results so far. Good luck!