The potency depends on the strain, and how well you treat it. Autoflowering strains are made by crossing usually an indica with a ruderalis (hemp) although that's as much as I've ever bothered to find out on the subject, I would suspect the hemp genes would limit the potency somewhat, although proper selective breeding would bring out desireable traits like increased resin production etc.
Autoflowerers never really interested me, I like to be able to plant a couple of seeds of a strain, get a female and take as many clones as I like for as long as I like without having to shell out for more seeds every grow.