I only trimmed a few leaves for more light to lower canopy ( near vert grow ) but didnt touch em really til she started to flower and sum buds were totally by fan leaves bigger than my hand..and i already had sum tied down. My advice is to not trim those big leaves til they either yellowing or diseased, tie em, tuk em whateva but your plant needs those big leaves. When ur plant is nearly done it may appear to have many little leaves in comparison, but they are part of the buds usually.