Yep, especially if you consider the cost over a year. Let's say that you were trying to light a 4x4 space. With LM301B diodes you could get away with 450watts of lighting, but with LM281B+ diodes you'd need 600watts for the same photons (plus you get more heat along with that extra wattage). If you are paying 20 cents per KwH, that difference adds up to $120 over the year, just for a 12/12 lighting cycle. For 18/6 in veg, it's close to $200 more you would pay in power over the year. Everyone's power costs are different tho.