Personally I'd run 8 plants, and grow myself some organic monsters.
BioCanna BioTerra on the BioCanna Vega and Flora line. I would amend the soil with oyster shell for calcium, AN Great White for biologicals, and GH Rare Earth for humics and silicon. I would supplement my grow with some of Humboldt Nutrients' products like Sea Mag, Flavorful, and Honey ES. I would also use Canna Rhizotonic, CannaZym, PK 13/14, and Boost Accelerator.
I'd go with 12 fem'd seeds, something like Sour Kush, Cole Train, Lemon Skunk, maybe True Blueberry. I'd be aiming for a hybrid with vigor and high quality taste and smell. Quantity isn't my goal really, not with 2000w, I could grow enough for an entire year of personal consumption on that system in just 4 months.
My 8 plants would be made to be bushy. I would start them with day light CFL bulbs up to maybe the 4th or 5th node. Then I'd transplant, defoliate, and begin using HID lighting. Once the plant had rebounded I would fimm after the 6th or 7th node. I'd also top the branches as they exceed the main stalk height. I may defoliate 2 more times during veg, and if possible fimm the main stalk branches as well. This should require a week extended vegetative period for each rebound, and 2 months (8-9 weeks) sounds like an appropriate amount of time to reach 24" to 28" tall. Each plant will have dozens of well developed tops, and should be fairly uniform and even. I would anticipate 10 weeks of flower for the quicker strains and up to 14 weeks for the longer ones.
They would be started in party cups, transplanted to 2 gallon SmartPots and finished in 10 gallon smart pots that have been rolled down so they only contain 6-7 gallons of soil (about 20 liters). My thought is about 1 liter per week of life. The width of the 10 gallon planters allows for the roots to really stretch out to support these soon to be top heavy bushes.
That's what I'd do, in soil, with these lights. Coco, or just hydro, is a totally different story.