If weed isn't properly dried I will get a fat headache and sore throat after smoking it that lasts for hours. You need to not only make sure the buds are ready to harvest but more importantly cure and trim it properly. Some really leafy Thug Rose I grew gave me a sore throat every time I smoked it cause it dried too fast due to genetically airy buds and it had a lot of leaf on the buds. Plants right next to it were chopped at the same time and took an extra 4-5 days to dry and were way smoother no sore throat or weird stuff like that..