I don't know anything about those nutes in particular. You ppms might be a smidge high. At 2-3 weeks, 300ppm would be just about right, 4 weeks (400), 5 weeks (500) up to 8 weeks, then hold at 800 ppm for flowering. At least that's the way I do it. I have just a basic 3-part nutes kit from Advanced Nutrients, and I add cal/mag as the ppm of my water is a little low (140) and therefore I'm a little light on the cal/mag from the water.
Since the plants look healthy otherwise, why don't you back off the ppms to 300 for a couple of days and see if that doesn't stop the spreading of the spots. If no new spots develop, then it might have been over-feeding. If the spots continue to spread, then it's something else. The spots you have won't get better -- they'll stay the same even when you fix the problem. But the problem won't continue to new leaves.