"There were other novel substances as well. Leonard [Pickard] made a new LSD analog called “diazedine,” though I don’t know exactly what that was either."
Are you familiar with lysergic acid 2,4-dimethylazetidide?
"No, but they were calling this diazedine. It was also crazy, but nothing earth-shattering. Leonard [Pickard] gave it to Todd [Skinner] in a bottle of Everclear for testing, and we would dose a capful at a time.
Apparently, diazedine failed to be doable on a large scale because the production costs were too high and the yields too low. Diazedine caused a lot of stress between Todd and Leonard, because they had high expectations for it as an LSD alternative."
Lysergic acid 2,4-dimethylazetidide (aka LSZ) belongs to a very small group of serotonergic psychedelics that surpass LSD in potency. Aside from the fact that “diazedine” is a lexical clipping of dimethylazetidine (diazedine<dimethylazetidine), the first paper describing the chemistry and pharmacology of LSZ came out of a laboratory at Purdue University, where Leonard had previously studied under the renowned chemist David Nichols. Though the paper was published after Leonard’s arrest, it is still quite likely he was aware of the preliminary research. When I asked Dr. Nichols whether he thought Pickard may have produced LSZ, he replied, “Leonard knew of our work, of that I am certain.” Rumors of LSZ distributed on blotter paper (purportedly under the name λ) have circulated for years, though there are few confirmed reports of its existence. Of course, the name diazedine is ambiguous and could be referring to just about anything, but I would bet a kilo of benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate that LSZ and diazedine are one and the same.