Yeah, that's what it appears like, some biological function that's critical to photosynthesis just shuts down for unknown reason(s).It would be dependent on what mutation the plants have undergone (if any). It could be something that only happens in flower, or it could be a combination of small mutations that finally shut down a biological function (inability to assimilate N, P, K, or micronutrients) or weakend chlorophyll/chloroplasts, a disruption in transport of nutrients within the plant, no way to really know, but it's a possibility. Try growing from seed or get a diffent clone strain and see if the problems persist, then you'll know with greater certainty.
I don't have the time or the space to try growing from seed, but that is a good idea thank you.