NEIN! Don't release the lady bugs until after a couple of days after you spray whatever you spray....and be sure to do a couple of treatments.... then spray down the leaves with water to rinse them.... THEN release the ladybugs.... kind of like sending in infantry to occupy and clear the area after carpet bombing....
and here is a cut and paste of the recipe I use
Tobacco Spray for Insect Control
Nicotine is extremely toxic to insects but it's effect is short-lived, only a few hours. This makes it a low hazard to your good insects such as bees and lady bugs.
This is a good defense against aphids, fungus gnats, immature scale, leafhoppers, thrips, leaf miners, and asparagus beetle larvae.
4 cups water
1/4 teaspoon plain liquid dishwashing soap
1/4 cup dried crushed or chewing tobacco or cigarette butts
1.Add the soap to the water and stir to dissolve
2.Soak the tobacco or cigarette butts in the water and soap mixture for 1 hour.
3.Strain through cheesecloth or other fine strainer to remove particles that would clogg your sprayer
Pour into a hand sprayer and spray directly onto pests and undersides of leaves. Use weekly.
Store in tightly closed container. Will keep several weeks.
Note: nicotine can be absorbed into the plant leaves and remain for several weeks. To be safe,
do not use on vegetables and fruits plants sooner than one month before harvest.
Do not use on eggplant, peppers or tomatoes, as these plant suffer from many of the same diseases which tobacco may carry.
Wear gloves and a respirator.... this stuff is pretty bad fer ya