Get HIGHER LONGER Off LESS BUD With OTC Pill

this seems to be legit to some extent. first, there is a risk to overuse of cimetidine. you will compensate for it and will develop chronic heartburn over time that you will chronically take cimetidine to fix 24/7. one addiction will chase the other so to speak. 2. there could be a lot of different chemicals that could work on this enzyme that may be better or worse than cimetidine. 3. your thc tolerance may increase over time as your dosage effectively increases. 4. there are always a million+1 risks when it comes to anything medical so, as always, be smart.

buzz kill.....but a very good point.. drive your tolerance up and you're gona end up worse. best to just quit for a month to kick some of your tolerance

CYP2C9 - Wikipedia, the free encyclopedia

Selected inducers, inhibitors and substrates of CYP2C9[1] Substrates Inhibitors Inducers Often mentioned [2]:

• NSAIDs (analgesic, antipyretic, anti-inflammatory)
  • celecoxib
  • lornoxicam
  • diclofenac
  • ibuprofen
  • naproxen
  • piroxicam
  • meloxicam
• phenytoin (antiepileptic)
• fluvastatin (statin)
• sulfonylurea (antidiabetic)
  • glibenclamide
  • glimepiride
  • glipizide
  • tolbutamide
• angiotensin II receptor antagonists (in hypertension, diabetic nephropathy, CHF)
  • irbesartan
  • losartan
• S-warfarin (anticoagulant)

Other:

• sildenafil (in erectile dysfunction)
• terbinafine (antifungal)
• miconazole (antifungal)
• amitriptyline (tricyclic antidepressant)
• pitavastatin (statin)
• rosiglitazone (antidiabetic)
• tamoxifen (SERM)
• cannabinoids (psychoactive)

Strong [3]:

• Benzbromarone
• sulfaphenazole (antibacterial)
• fluconazole (antifungal)
• Valproic acid (anticonvulsant, mood-stabilizing)

others:

• amiodarone (antiarrhythmic)
• cimetidine (H2-receptor antagonist)
• fenofibrate (fibrate)
• fluvastatin (statin)
• fluvoxamine (SSRI)
• isoniazid (in tuberculosis)
• lovastatin (statin)
• probenecid (uricosuric)
• sertraline (SSRI)
• sulfamethoxazole (antibiotic)
• teniposide (chemotherapeutic)
• voriconazole (antifungal)
• zafirlukast (leukotriene antagonist)

Often mentioned [2]:

• rifampicin (bactericidal)

Other:

• hyperforin (constituent of St John's Wort)
• secobarbital (barbiturate)
• aprepitant (anti-emeti

Finally picked up some of this stuff today. Just took 800 mg (4 pills). Got the generic, cimetidine. $7 for a bottle of 60 at Wal-Mart. Anyway, I'll toke it up in about 30-45 minutes and let you all know how it goes.

Not a good idea to take pharms unless nessacary, kid.

howd it go zardokk?

...maybe hes so much higher he forgot to post

lol. i hope so....

zard? you there?

well, i know this much, at the very least he just got high and didn't have hearturn for the day.lol.

Haha, I didn't get any heartburn and no real weird side effects. The pills themselves made me a tiny bit spacey, but not really a big effect, definitely nothing that would attribute for the extra high effects. As for the high...I only had about 1 bowl worth of bud left, which I split with my girlfriend. I got pretty damn stoned. It was high quality kush, but still, I only got about 3 hits and I'm a fellow with a decent tolerance...Anyhow, I did seem to get a fair bit higher than usual, but the most pronounced effect was that the "peak" of the high lasted a lot longer than usual. I didn't get THAT much higher than I thnk I otherwise would have (although I was pretty ripped off 3 hits, so who knows), but it definitely did last longer. The "peak" for me usually comes on around 30 minutes or so after smoking, and wears off within an hour and a half or so. This time it lasted for around 3-4 hours, no joke. Toked around 3 PM, was high until around 10. Definitely an interesting drug here, but I wouldn't recommend doing this more than occasionally, as there could quite obviously be side effects from long-term use of a 4x dose of any OTC pill, regardless of what it does.

HOLY BALLSACK! NEW, IMPROVED RESULTS JUST IN! I think the first attempt might've actually been mostly placebo effect. I've just tried this Tagamet (cimetidine) trick for the second time, and WOW! I don't even just mean WOW!, more like WWOOOOOWWWW!!! I really haven't been this high in quite some time. I hit around the normal amount of bud I always do (3-4 waterfalls just FYI), but I took 4 Tagamet about 45 minutes before toking. Let me tell you motherfuckers...this shit really works. I didn't even feel drugged from the Tagamet whatsoever, I took them, then felt pretty much 100% normal, toked up, and KABAMALAMA! This feels like some of the first few times I got high. Hopefully some of you guys know what I mean. Those first times I wasn't even high, I was in a whole other fuckin' world, man. But this is real close. Got me feelin' RIIIIIIPPPPPPPPEEEEEEEEDDDD!!!!!!!!!!!!!!!!!!!!!!!!!!!

Sweeeeet! I just happened upon this thread then ran straight out to wal-mart and got 30 tagamet for $7. I popped 5 just for good measure. In 45 minutes I shall smoketh and record my results for the purpose of scientific research...I hypothesize that I will be pretty fuckin stonewalled.

I'm outta control stoned right now...struggling to type.. this shit really seems to work. Not the highest I've ever been though. And I do agree that it could be really hard on the liver if I were to take the pills on a regular basis. It really brings out the euphoric feeling like the first time I ever got high...cool stuff. Good body buzz...smoked the finest northern lights. Just slammed a large dean's milk chug. It feels like I'm actually getting higher as I type this, and as I go on typing this I find that I'm typing slower and slower and it feels like I've been typing forever now so later guys

Update: I smoked one bongload at 1 a.m last night, and it is now 7:41 pm here. It's been over 18 hours since I smoked, and guess what, I STILL feel high. I was still pretty ripped when I got up today, and its been dissipating very, very slowly over the day. It's not near as intense as when I first smoked, but it definitely feels like I just took a couple of bong rips at least. This stuff is incredible, I can't believe I haven't heard of this until now! Maybe there's just a little placebo effect involved at first because the intesity of a marijuana high does depend a lot on your state of mind, but I can guarantee you 100% that the cimetidine does make the thc seem stronger and lets it linger for what seems like forever.

Basically, from what I understand, it just prevents THC from being broken down by a particular enzyme because the body uses the enzyme to break down the cimetidine first, though I'm not totally sure why, I guess just the chemistry of the substance. I've tried this technique several times since I initially made this thread, and I have concluded that Tagament makes the high slightly stronger, it makes the come up take longer (make whatever bud you smoke with it seem like hardcore CREEPER, at least IMO), and it makes the high last a LOT longer. Typically when I smoke, I'm high for anywhere between an hour and four hours, depending on how much I smoke. When I take 4 cimetidine pills (800 mg total), I'm high for anywhere between like 4 and 6 hours, with a stong sort of after-high that seems to last for a while. This stuff is definitely good, I wish a some other people here on the forum would try it. I guess maybe my title to this thread put people off...?

I know that when we were back in highschool, usualy if we wanted to get really high and all we had was a gram, we would take a couple benedyrl pills. I'm not sure exactly how that works, but it helps to make you ripped.

this is pretty interesting. I'm not thinking of this in a sense that 'oo get higher' more like in a scientific sense that this could actually work quite well and could be good for a once in a while thing for those chronic smokers among us. who knows though, this may also be a way to increase your tolerance, as the weed lingers longer. but perhaps this isn't the case, either way I think some chemists should get some info on this.

This might sound stupid but could taking this pill make it possible to OD? Cause if THC is floating around your body not getting taken out for hours and you smoke an ounce of chronic...? I'm gonna try it with "chronic" and reg just to see how high I can get off some shit weed :0

poplars said:

this is pretty interesting. I'm not thinking of this in a sense that 'oo get higher' more like in a scientific sense that this could actually work quite well and could be good for a once in a while thing for those chronic smokers among us. who knows though, this may also be a way to increase your tolerance, as the weed lingers longer. but perhaps this isn't the case, either way I think some chemists should get some info on this.

Click to expand...

damn stoner homophones...

do you mean chronic as in often or chronic as in chronic buds? or both? I'm assuming the latter. But still confused me

Any news from anyone else who's tried this? I'm curious to see what results you're all getting. Myself, my girlfriend, and a few friends of mine have all tried this and confirm that it works. The Tagamet is also useful if you have heartburn, although one pill is sufficient if that's the case.

what are the side effects of tagamet?

I mean if 1 is recommended for heart burn you are taking 4 times the normal dose.....that cannot be good for you