Hey..... throw 50 seeds in- hope for 20-25 females, clone your females and then flower them (1 1/2 month veg), keep everything labeled so you can keep track of your phenotypes. 1 1/2 month veg should allow for between 5-10 great clones from each mother. The space will become available that you need for flowering the seeds as the males are culled out. As the plants flower you will be able to select your favorites, or keepers, and then keep their healthiest and most promising 1st generation clones as mothers for future generations, then flower out the rest of your first generation of clones.
Once you have finished those two flower cycles you will have narrowed down and dialed in your strains, growing methods, and have the two styles of growing to compare- fewer larger plants in the first run, and a bunch of smaller plants in the second.
You can use 2400k to run that space- 4 600W's- or two 1000s on movers and a center stationary 400.
My personal recommendation would be to continue the 1 1/2 month veg cycle on your clones, as this gives them time to root, become established, and have more growth for higher yield- while the mothers are in flower (cant flower them till the moms are done right?). Naturally the clones will be a bit smaller because of root time, transplant adjustments, and they are clones and dont retain quite the same of vigor as their seedmothers, most of the time anyways.
Anyways- doing this brings yields faster, 3 1/2 months compared to 5 if you mother and take cuts before flower- 2 yields in roughly the same timeframe doing it this way and along the way you narrow down your growing method. Hydro, DWC, Soil, doesn't matter, schedule lighting etc would be about the same.
Just make sure you have a really nice climate control system going on- whether by automation or by having a balanced and consistent run- your humidity will spike running sealed room ops like this, air flow is key, make sure you keep on top of that, and air exchange.
Personally I would do soil, that's just me- makes all phases of transition easier and a bit more predictable. Best of luck, I too would like to see it as you complete it.... am throwing around some flowering room options myself....