Sounds pretty good, hope to see pics soon!
I recommend using the 2 - 1000watt lights in your flower room and the 2 - 600's in the other rooms.
Your flowering plants are no doubt going to be bigger then your vegging ones.
So, your gonna want greater penetration and a larger footprint in your flowering room.
You have the larger footprint already, but not greater penetration!
As far as the A/C goes, Do you have CH/AC?
If so, the best way to go is to tie into this.
If not, the second best would be a dual-hose stand-up A/C.
This is because A/C's use a compressor, which generates heat and needs to be as far out of the environment as possible.
I'm not sure on what size unit would be right for you but I would buy something rated 30-50% bigger then your room.
Keep in mind that a sealed room still needs to be exhausted at dark to remove the CO2. This is because plants can no longer break the CO2 molecule with photons, and needs simple O2.