Yes,wild hemp can be crossed on other strains and in many ways it is preferable to crossing those other strains with ruderalis. Bigger plants,more production,good thc content,and resistance to native pests,fungus,and diseases.
If you cross a strain with ruderalis you will be making a a variation of a auto flower which diminishes the production of buds intensely, since it is now a time sensitive plant not a photo period plant. Good thc content.... 1-2% is good thc content? Here's a little something from when Nevile experimented with crossing strains with ruderalis.
Early efforts
"Perhaps the most known efforts to incorporate Ruderalis traits into drug hybrids are those of Nevil, proprietor of the original Seed Bank, and the person largely responsible for the original dispersion of many of today's drug varieties.
Nevil experimented with crossing Ruderalis strains to plants such as Mexican, Skunk#1 and several Indicas, in hopes of combining the early flowering of the Ruderalis with the potency and flavor of the others.
Although some of Neville's crosses matured much earlier than previous marijuana strains, they tended to be low in potency, unstable in terms of maturity, and often sported buds that were leafy with shrunken calyxes."