If I were growing in a 2.5 x 2.5 then I would just do one plant and veg it a little longer so I could train it to grow short and wide so it fills the tent. You can do more, and have a shorter veg time, but it's more work. My first grow was 4 plants in a 32" x 32" (which is basically the same size) and humidity was a bitch to control with all those plants in there. You can definitely do 2-4 plants in there, though, it just gets tight.How many would you grow at once?