Always. The PH perfect nutes seem to work well when the water out of you tap is a low ppm. Mine is 100-110 depending on what tap I use. Ive used the PH perfect 3 part and also their 2 part for coco and didnt have to adjust PH unless using silica, which is usually the case anyway. Its all basically the same, AN just has a lot of wanky marketing and IMO way too many products which makes people think you need all of it.
Good base nutes, and a couple additives like CalMag, some type of simple sugar, PK booster, and a Mag-Sulphur product for ripening(Floranectar, Botanicare Sweet, etc). 2-3 week flush with simple sugars and enzymes. Bob's your uncle