It's best to do it at the beginning of the night.Jay - I'm a first time grower so take this with a grain of salt... are you watering, feeding, or spraying Neem onto your leaves during the hot part of the day? If so, not a good idea because when the droplets get on the leaves, the sun will burn typically "round" holes.
that is "leaf muncher" damage, either caterpillar or grasshopper type of bug, you need a better cage, hopefully its not catterpillars,Roughly 9-10 weeks.
Recently transplanted and is looking much healthier. Does it look healthy/normal? Although the bottom leaves have some holes..? It's about two feet tall currently. Thanks I appreciate feedback