No, not really if you do this first. Once your soil mixture is ready to be added to your pot, fill it completely. Then saturate the media with PH'd or ready to go water completely and allow it to stand for at least 2- 3 days before putting in the seed or seedling. Once the seed or seedling is in place, some put a small dome over them some don't. This can be a cut water bottle or plastic clear cup or actual dome. If using any type of dome, be sure and take the dome off at least twice a day for about an hour, to allow the plant to be exposed some and avoid damping off.
You should not have to add any water or mist for at least 2 weeks, this method helps avoid over watering and allows the seedling to develop it's roots while absorbing the humidity created by the pre-wet soil release of moisture. Rarely have I had a seedling fail using this method.