Two hugely important things I don't see talked about enough in relation to pest and disease prevention are overall plant health and growing the right strain for your environment.
Weak, unhealthy plants are not nearly as good at fending off the ever present risk of pests and disease as a healthy plant is. Obviously a optimal environment and proper application of water and nutrients are the biggest things any grower can do to insure plant health, but there are some other things you can do to improve health and vigor.
One of the most overlooked of these things is adding Si to your nutrient regime if you are growing in any kind of hydroponic or soil-less medium. Living soil typically has ample available Si, but it is an absolute game changer for hydro. Promotes stronger, healthier foliage and gives the plants a huge benefit in fending off insects and fungal infections.
Anyways, sorry for rambling on.. in terms of prevention products I've had really good luck with Method One PPS. It is all natural, can be used pretty much as often as you want with no risk to plant health, and doesn't seem to leave unpleasant (and possibly unhealthy) residue behind like some of the spay on products I've tried in the past.