Aye, the only problem I'm running into is space. I want to go LST but my limitation is area (want to have 2 plants constantly flowering every 2 weeks) not height. What's your experiences with pruning the bottom leaves?
I try not to cut off any fan leaves because they're a precious commodity... the ones that can't get light will die off anyway on their own accord, and can then be removed. If you have stress issues of any kind along the way you may lose fan leaves inadvertantly... and if that happens you may be wishing you had not been so prune happy earlier on.
Many people prune lower bud sites and new developing foliage (while still tiny) at the bottom during flower to prevent popcorn buds from forming underneath and to prevent the plant from wasting energy growing leaves that won't get light anyway. This is a reasonable action, but it's pretty debatable as to whether or not it actually increases the yield in the upper buds... so my approach has been to just let the popcorn grow. I don't mind airy buds, I still smoke 'em. But if not desired, they make excellent hash, so I don't know why anyone would bother personally.
Also, fractional harvesting can help a lot... that's cutting all the well developed bud off in one harvest, then moving the light closer to the now-exposed popcorn bud for another couple weeks so it can full up a bit. I did this last time and ended up pulling an extra 3 oz... seemed worth it to me.