I have a 5 by 7 room (8ft ceiling) completely sealed. I control humidity with a humidifier and using LEDs, have no heat issues (range is from 74 to 84 degrees). I have a CO2 data logger for continuous CO2 monitoring. I am using the fermentation method with 2 small carboys and a standard stopper that allows the CO2 to vent thru a water chamber - all standard wine store equipment. Each is filled with 10 litres of pure water, 2 dry litres of sugar, one multi-vitamin tablet, 2 tsp of yeast booster and 2 tablespoons of regular bakers yeast. The specific gravity starts a 1.08. The theory is that bakers yeast promotes more vigorous fermentation but is killed off a lower alcohol concentrations (I've yet to prove this, but it is cheaper than wine yeast). Prior to logging the CO2 data. I generally replaced the carboy when I saw no more signs of bubbles thru the stopper and found the specific gravity was about 1.02, so there's still sugar in the mix but the alcohol is killing off the yeast. Using a wine yeast, you could get the sp gravity down to 1.00 but it's expensive and releases more slowly.
The data logger records CO2 levels of between 2,000 ppm and 3,500 ppm depending on the time of day and how recently the carboy was refreshed. I've only had the data logger for 1 week so I'm still trying to work out the best combination of carboys and fermentation materials. Both carboys were refreshed the day I started using the data logger and are still cranking out good amounts of CO2. I'll refresh them when my morning CO2 levels are down to 1200ppm.
What's interesting is that my portable closet nursery is in the furnace where there's a pilot light for the natural gas hot water tank and one for the natural gas boiler and the CO2 readings are 850ppm - which I figure is enough for veg. That room is not sealed but neither is there any effort to vent it. I can see advantages to a CO2 tank in a sealed room but will hold off buying one until I see if I can control the fermentation process. Carboys do take up room that could be filled with plants.