Novel coronavirus introduced to humans in exotic animal meat market.

Fogdog

Well-Known Member
But is there a difference between a stuffy nose and a runny nose and could that just be the bodies reaction to the virus like the doctors eyes?
I listened to an interview from that doctor (or maybe it was a transcript from an interview). The doctor talked about his own experience, which was, he recalls touching his face near one of eyes and it later became red, as in, inflamed. He later came down with the disease and he said he thought the infection entered through his eye. That's how I recall it. It's not a very controlled study. Hard to draw general conclusions. In my opinion.

Maybe we can just lump "stuffy nose, runny nose, other symptoms associated with head colds as one form or another of nasal congestion?
 

DIY-HP-LED

Well-Known Member
The initial symptoms may vary some depending on were the virus enters the body, if you breath it in you may start with a cough, the nose may run if it enters there or the eyes become red and runny.
Had a head cold for the last few weeks, many people in town have it too, a slight infection, but persistent. Treat everybody like they have the plague including yourself. I haven't been down to visit my sister in an assisted care home for two weeks because of it (my choice) and the other day they closed the place to visitors because of the pandemic, I might not see her again.
 

captainmorgan

Well-Known Member
I guess what I'm saying is, depending on where the virus enters the body can it cause different reactions and not call it a symptom. The symptoms are what it does once it's in the lungs.
 

DIY-HP-LED

Well-Known Member
I guess what I'm saying is, depending on where the virus enters the body can it cause different reactions and not call it a symptom. The symptoms are what it does once it's in the lungs.
I believe the virus attaches to ACE2 receptors on the cell membrane and these receptors are most abundant on cell surfaces in the lower lungs. That's why it moves there quickly and sets up housekeeping. This should answer some of your questions
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Coronavirus Pandemic Update 37: The ACE-2 Receptor - The Doorway to COVID-19 (ACE Inhibitors & ARBs)
 

Fogdog

Well-Known Member
I guess what I'm saying is, depending on where the virus enters the body can it cause different reactions and not call it a symptom. The symptoms are what it does once it's in the lungs.
Is this something you know or are speculating about? I'd be interested in reading about this if you have information to share.
 

DIY-HP-LED

Well-Known Member
I guess what I'm saying is, depending on where the virus enters the body can it cause different reactions and not call it a symptom. The symptoms are what it does once it's in the lungs.
Sorry captain, I never watched that one yet and figured he'd mention the concentration of the AC2 receptors in the lower lungs, this one deals with hypertension meds and coronavirus. I believe he covers it in one of the earlier videos in this informative series.
 

captainmorgan

Well-Known Member
Is this something you know or are speculating about? I'd be interested in reading about this if you have information to share.
I'm speculating from bits and pieces of things I've read, I know the classic symptoms once it's set up shop in your lungs but am wondering about lets call it signs you picked up the virus in your eyes or nose and not deeply inhaled from your mouth. Not that it would make much difference, especially since it's moving into spring and allergy season is here. The doctor that thinks he got it in his eyes says red, swollen, watery, burning in his eyes, that sounds like a allergy, does it do that in your nose?
 

captainmorgan

Well-Known Member
Sorry captain, I never watched that one yet and figured he'd mention the concentration of the AC2 receptors in the lower lungs, this one deals with hypertension meds and coronavirus. I believe he covers it in one of the earlier videos in this informative series.
Yep, I already know about the receptors.
 

Fogdog

Well-Known Member
I'm speculating from bits and pieces of things I've read, I know the classic symptoms once it's set up shop in your lungs but am wondering about lets call it signs you picked up the virus in your eyes or nose and not deeply inhaled from your mouth. Not that it would make much difference, especially since it's moving into spring and allergy season is here. The doctor that thinks he got it in his eyes says red, swollen, watery, burning in his eyes, that sounds like a allergy, does it do that in your nose?
I'm not all that into speculating on something I'm ignorant about. I try to stick to what is known and am not all that interested in lay opinions or speculation. I have tons of respect for you, Morgan. Just I'm not the kind to spend time on things about which I don't have any knowledge or information.
 

DIY-HP-LED

Well-Known Member
Yeah, abandon will probably scold me for speculating in his thread lol.
Here is the latest update Captain, he talks about the spread and mild or no symptoms. This one might answer your concerns, though I haven't watched it yet, (going to now).
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Coronavirus Pandemic Update 39: Rapid COVID-19 Spread with Mild or No Symptoms, More on Treatment
 

DIY-HP-LED

Well-Known Member
Yeah, abandon will probably scold me for speculating in his thread lol.
It looks like hydroxychloroquine is showing promise as a treatment, I'm sure someone is working up a sweat to get the paper reviewed and out. I wonder about the data from S Korea concerning this treatment, they used it and there's speculation about it contributing to their low mortality rate.

Good Vitamin D levels and this treatment if ya get it, might be the ticket to survival for many. Drugs like hydroxychloroquine are common in many poor countries and used for malaria, they could be deployed quickly if the studies show that it helps, this has the potential to help a lot of people and perhaps keep them off a nonexistent ventilator. Hope perhaps, from what I've seen of it, it looks like a viable option. It would only be an off label use too, it's widely available.


 
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captainmorgan

Well-Known Member
Here is the latest update Captain, he talks about the spread and mild or no symptoms. This one might answer your concerns, though I haven't watched it yet, (going to now).
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Coronavirus Pandemic Update 39: Rapid COVID-19 Spread with Mild or No Symptoms, More on Treatment
LOL, it's not really my concern. It's how my mind works, I'm a problem solver, as such I try to collect info and ideas. Most of my friends are at risk along with myself and having a handle on this might just help me of someone I know. Example is I talked with a friend today that has COPD, I was able to advise her to be careful with the meds she takes like only use Tylenol and I warned her about steroids and the virus. I had already got her taking vitamin D and told her to add zinc.
 

DIY-HP-LED

Well-Known Member
LOL, it's not really my concern. It's how my mind works, I'm a problem solver, as such I try to collect info and ideas. Most of my friends are at risk along with myself and having a handle on this might just help me of someone I know. Example is I talked with a friend today that has COPD, I was able to advise her to be careful with the meds she takes like only use Tylenol and I warned her about steroids and the virus. I had already got her taking vitamin D and told her to add zinc.
Check out the latest update, not hard on the head!
 

DIY-HP-LED

Well-Known Member
LOL, it's not really my concern. It's how my mind works, I'm a problem solver, as such I try to collect info and ideas. Most of my friends are at risk along with myself and having a handle on this might just help me of someone I know. Example is I talked with a friend today that has COPD, I was able to advise her to be careful with the meds she takes like only use Tylenol and I warned her about steroids and the virus. I had already got her taking vitamin D and told her to add zinc.
If you can delay getting this bug long enough, there might be treatment options that will increase your odds significantly.
 

DIY-HP-LED

Well-Known Member
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)

Abstract
Estimation of the prevalence and contagiousness of undocumented novel coronavirus (SARS-CoV2) infections is critical for understanding the overall prevalence and pandemic potential of this disease. Here we use observations of reported infection within China, in conjunction with mobility data, a networked dynamic metapopulation model and Bayesian inference, to infer critical epidemiological characteristics associated with SARS-CoV2, including the fraction of undocumented infections and their contagiousness. We estimate 86% of all infections were undocumented (95% CI: [82%–90%]) prior to 23 January 2020 travel restrictions. Per person, the transmission rate of undocumented infections was 55% of documented infections ([46%–62%]), yet, due to their greater numbers, undocumented infections were the infection source for 79% of documented cases. These findings explain the rapid geographic spread of SARS-CoV2 and indicate containment of this virus will be particularly challenging.
 

abandonconflict

Well-Known Member
WHO changed its stance on pet cats and dogs being susceptible to SARS-CoV-2. Cats and dogs do get infected. They're still saying they don't know if the animals can spread the disease (absence of evidence is not evidence of absence).

A dog in Hong Kong tested positive, subsequently tested negative, was released back its owner and died two days later. The negative test could have simply meant that there was no immune response. The positive test was a swab, they actually took a tiny tissue sample from mucous membrane in the upper respiritory tract and found infection. After testing in this way again and seeing nothing, along with no clinical signs of infection, they tested the dog's blood and found no antibodies, declared the pooch virus free.

Or, the dog could have died of stress and age. It's certainly possible.

Don't let your cat out. Don't let people touch your dog.
 

abandonconflict

Well-Known Member
Inflection points are what to look for, when you seek statistical proof that everything is going to be ok. So, you take them old numbars and graphicalize em up, new cases per day and whatnot. Here's what may be a best case scenarion demonstrating what I'm failing utterly to explain:
Screenshot (49).png
As you can see, in the last couple weeks of February, numbers started exploding. South Korea had already implemented its effective and efficient strategy to combat the outbreak weeks earlier. That line wanted to get steep. In early March, which was quite soon and early, that line started wanting to get horizontal. That's the inflection point. Because of their prudent counter measures implemented before things got scary, the line began to flatten pronto. It doesn't mean they all start going out to the disco again and raving. It means there's a light at the end of the tunnel and this too shall pass.

Now here's a worst case scenario. Italy's numbers started exploding around the same time AND THEN they implemented protocols.
Screenshot (51).png
Still no inflection point. They now apparently have more fatalities than even China.

Please observe social distancing and don't be a super-spreader.
 
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